Crohns.net
June 2012
Pamela Nathan

Crohn's Disease Linked to Jews of Eastern European Descent

A team of researchers from Mount Sinai School of Medicine, led by Inga Peter, has identified that Crohn's disease, (a chronic inflammatory disease of the intestines) has been linked to five new genetic variants in Jewish people of Eastern European descent (Ashkenazi Jews). These findings will help to better understand why the occurrence of Crohns is almost four times greater in Ashkenazi Jews than in other populations.

The study is published in PLoS Genetics. Earlier investigations had discovered 71 genetic mutations of Crohn's disease risk in people of European ancestry. The researchers used DNA samples from 1,878 Ashkenazi Jews with crohns disease, and 4,469 Jews without Crohn's disease, in order to analyze their genetic make-up in this study. The team discovered 5 new genetic risk regions on chromosomes 2, 5, 8, 10, & 11 (specifically regions 2p15, 5q21.1, 8q21.11, 10q26.3, and 11q12.1), in addition to 12 of the known risk variants. Read more

7 Steps to Treating Diabesity

Mark Hyman, MD, in his book, "The Blood Sugar Solution" refers to the term "Diabesity" i.e. an overwhelming epidemic of obesity and type 2 diabetes. He talks about ways of treating this significantly risky condition.

1: Boost Nutrition
The main driving factor - of our diabesity epidemic is our nutrient poor, calorie-rich, low-fiber, high-sugar Standard American Diet. This has led to a nation of overfed but yet undernourished people. There are so few nutrients in our diet that we now have an epidemic of nutritional deficiencies that promote the development of diabetes, including vitamin D, magnesium, chromium, zinc and antioxidant deficiencies. Whole, real fresh food that you cook yourself is the most potent medicine you can use to prevent, treat and reverse diabesity.

2: Regulate Your Hormones
Sex hormones, adrenal or stress hormones & thyroid hormones, are important if you want to heal. They are all interconnected; they interact with one another like a big musical symphony. When this symphony is playing out of tune, problems arise. To overcome diabesity, you must identify and treat thyroid imbalances that control your metabolism, overactive stress hormones that worsen insulin resistance and blood sugar, and insulin imbalance and its harmful effects on your sex hormones.

3: Reduce Inflammation
Anything that causes inflammation will, in turn, cause insulin resistance. And anything that causes insulin resistance will cause inflammation. This dangerous spiral is at the root of so many of our 21st-century chronic maladies. Sugar, refined carbohydrates, trans fats, too many inflammatory omega-6 fats from processed plant oils (like soybean or corn oil), artificial sweeteners, hidden food allergies and sensitivities, chronic infections, imbalances in gut bacteria, environmental toxins, stress, and a sedentary lifestyle all promote inflammation.

Of course, which of these factors is the source of inflammation for you is a key question, and the answer is different for everyone. Locating and addressing each of the sources of inflammation in your life is essential not only for overcoming diabesity, but also for addressing virtually every other health-related issue. Read more

Probiotics May Prevent Eczema

Cutting edge research led by University of Otago researcher Dr. Kristin Wickens, is showing that probiotic use halves the risk in the prevention of eczema among high-risk infants.

Dr. Wickens and her colleagues at the university's Wellington campus and at Auckland, where research has been led by Auckland University paediatrician Prof Ed Mitchell.

The study showed one probiotic, involving a bacterium named Lactobacillus rhamnosus HN001, lowered the risk of developing eczema by the age of two, by about half, among young kids who were at high risk of developing allergic disease.

Probiotics are microorganisms that prevent disease and protect their host. The probiotic found to be successful was developed by Fonterra. Read more

Did You Know...

  • Aspirin Therapy is Dangerous
    Aspirin therapy can be dangerous for healthy people, warns cardiologist Kausik Ray,MD. Many people take aspirin regularly to prevent heart attack and stroke.
    Recent Finding: Regular aspirin use in healthy people increased the occurrence of serious internal bleeding by 31% but had no significant effect on fatal heart attacks or any type of stroke. If you are on aspirin therapy, talk to your doctor. Do not stop it on your own.
  • Make Sure to Wash Fruits & Vegetables Thoroughly!!
    Apples top the "Dirty Dozen." Apples are number one on the list of produce that is most contaminated with pesticides, followed by celery, strawberries, peaches and spinach. The "clean 15," which are lowest in pesticides, include onions, sweet corn, pineapples, avocado and asparagus. Buy organic if choosing from the dirty dozen.
  • End-Of-life Palliative Care can Extend Life
    Giving patients with terminal lung cancer pain relief and other treatments to improve their final months not only made them happier and more mobile but also led to an average of about three months of added life. Patients receiving this care reported less depression and scored better on scales measuring pain, nausea, worry and other problems.
  • IUD's Reduce Cervical Cancer Risk
    Women who used an intrauterine device (IUD) for birth control had only about half the risk for cervical cancer, compared with women who had not used one. Research suggests that IUD's- possibly because they cause chronic low grade inflammation- may boost a woman's immune system, helping to fight off human papilloma virus (HPV) infections that can progress to cancer.

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