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VSL3 Questions Answered

How long do you need to wait for VSL#3 to work?

Usually, VSL#3 takes about a 1 week to establish in the digestive system.
VSL research study shows that maximum bacterial colonization of the digestive tract occurs in 20 days.

This high level of colonization will maintain if you continue take VSL consistently on a daily basis.

If you disrupt daily intake, the strains in VSL#3 are able to survive in the gastro intestinal system for up to 3 weeks.

Is it possible to take too much VSL#3?

Generally speaking probiotics and VSL#3 more specifically, have an remarkable record of safety.
VSL#3 probiotics is “Generally Recognized As Safe” (GRAS) for the dietary management of particular medical conditions.

What if I experience symptoms of bloating?

Mild bloating sometimes occurs during the first few days after starting to use VSL#3 probiotics. This is usually a transitory phenomenon due to the changing intestinal microflora.
If you experience bloating, you may find it necessary to reduce your daily intake. This will allow for this adjustment.

Are VSL#3 probiotics safe for children?

VSL#3 was determined to be Generally Recognized As Safe (GRAS). VSL#3 research studies show its efficacy for the dietary management of pediatric Ulcerative Colitis – UC and Irritable Bowel Syndrome – IBS.

Can I use VSL#3 probiotics while I’m taking antibiotics?

VSL#3 probiotics can be taken with all kinds of drugs. If you take it with antibiotics, it will not harm you, but the effects of VSL#3 may be lesssened because the antibiotics do inactivate the microorganisms in VSL#3. Continue to use VSL#3 once you havve completed the round of antibiotics.

How does VSL#3 differ from other probiotic products on the market?

VSL3 is a high potency probiotic formula made up of eight different strains of live bacteria that have been carefully cultivated and mixed in a ratio that maximizes the probiotic content. The highest number of bacteria and the unique choice of strains gives VSL3 a dramatic degree of potency.

It has been said that VSL#3 capsules are about 10-100 times* more potent than the average probiotic.
[*Source: AC Nielsen, Dec. 2009. Average bacteria claimed by product manufacturers was between 1 and 10 billion per capsule or tablet]

How do I take VSL#3?

VSL#3 comes in capsules and powder packets. The powder packets may be mixed with cold water or food and consumed. VSL#3 packets have a lemon cream flavor or are also available unflavored with corn starch added for stability.

VSL#3 should be stored in a refrigerator.

VSL#3 packets should not be mixed or consumed with hot drinks or foods as the heat can inactivate the bacteria.

Is VSL#3 gluten free?

Yes, VSL#3 is gluten free as defined by the proposed FDA definition of a gluten free food (F.R. Jan 23,2007 Vol.72, No.14).
The capsules are made of hydroxypropyl-methylcellulose (HPMC) which is 100% vegetable cellulose and meets the strict dietary needs of consumers that choose a vegetarian lifestyle.

How much VSL#3 probiotica should I consume?

Clinical studies that have evaluated VSL#3 probiotics for the dietary management of Ulcerative Colitis (UC), an ileal pouch or Irritable Bowel Syndrome (IBS).  Varying daily amounts of VSL#3 are used , from 225 (1/2 packet or 2 capsules) to 3,600 (8 packets of VSL#3 ) billion bacteria.*

The recommended intake of VSL#3 for adults and children is listed below. It ranges from 225 billion (2 capsules) to 3600 billion (8 packets) a day, or as directed by your health care provider.

Daily intake, based on studies performed are as follows:
Dietary management of gas and bloating in IBS 2-4 capsules or 1 packet
Dietary management of ulcerative colitis (UC) 4-8 capsules 1-2 packets
Dietary management of active UC  2-4 packets
Dietary management of ileal pouch (pouchitis)  2-4 packets

Recommended dosage for children intake by age (in years)

Less than 2 years
Dietary Management of active ulcerative colitis (flaring) – 1-3 capsules per day (open & add to soft food or beverages)
Dietary Management of ulcerative colitis (maintenance) – 1 capsule per day (open & add to soft food or beverages)

2-5 years
Dietary Management of active ulcerative colitis (flaring) – 2-3  capsules per day (open & add to soft food or beverages)
Dietary Management of ulcerative colitis (maintenance) 1-2 capsules per day (open & add to soft food or beverages)

6-11 years
Dietary Management of active ulcerative colitis (flaring) – 4-8 capsules per day (open & add to soft food or beverages)
Dietary Management of ulcerative colitis (maintenance) 2-4 capsules per day (open & add to soft food or beverages)

12-17 years
Dietary Management of active ulcerative colitis (flaring) – 2 packets per day (open & add to soft food or beverages)
Dietary Management of ulcerative colitis (maintenance) – 1 packet per day (open & add to soft food or beverages)
*Each capsule contains 112.5 billion live bacteria and can be opened to mix with any cold, non-carbonated beverage or any cold food and then consumed. Each packet contains 450 billion live bacteria.

What happens if VSL#3 probiotics are ledt at room temperature?

VSL#3 can be stored at room temperature (77°F) for up to two weeks without having any effect on potency. If it is left at room temperature for long periods of time or exposed to excessive heat, the number of beneficial bacteria in VSL#3 can become reduced.

Can I consume VSL#3 if I have intolerance to dairy products?

VSL#3 products may contain trace amounts of lactose [0.1g per 100g] and dehydrated skim milk or milk protein (casein and beta lacto globulin of less than 2mg/kg).

What is Maltose?

Maltose (malt sugar) is a disaccharide derived from germinated grains. It is formed when two simple sugars (called glucose) are linked together. It is added as a natural sweetener in VSL#3 products

Are VSL#3 products Kosher and Halal certified?

Yes. VSL#3 products are both Kosher and Halal certified.

Is VSL 3 Available in flavored powder in packets?

No, VSL 3 is only available in unflavored packets now.

How is VSL live bacteria probiotics ensured to keep potent?

Both the powder and the capsules have improved packaging to ensure keeping the probiotics potency.

The VSL#3 unflavored powder is put in triple layer packets. It ensures that there is no contamination. It also prevents light, heat, moisture from coming in.

The capsule bottle has a new and improved patented cap. The cap doesn’t let any wet or heat or even light enter the bottle. It also stops any contaminants from entering the bottle. There used to be a seonc seal on the bottle. They don’t need it anymore because of the newe and improved cap.


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