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Visbiome Research on Effects on Gut Microbiome

Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers

The purpose of the study is to evaluate whether the probiotic Visbiome Extra Strength reduces inflammation in HIV-infected men and women when compared to a placebo (inactive medication like a dummy pill).

The study will evaluate whether taking Visbiome Extra Strength by mouth for 24 weeks is safe and well-tolerated for HIV-infected persons on antiretroviral therapy (ART).

Probiotics are germs such as yeast or bacteria that are found in food and supplements that are used to improve the health of the digestive system.

Many people refer to probiotics as “helpful bacteria.” These bacteria live in the body and help the body work normally. In some medical conditions, including HIV infection, helpful bacteria are replaced with bacteria that can change the normal intestinal function and increase inflammation.

The investigators will test whether giving a probiotic can restore normal intestinal function and decrease inflammation.

This study is currently recruiting participants

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02706717

Verified July 2016 by AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)
Exegi Pharma, LLC
Information provided by (Responsible Party):
AIDS Clinical Trials Group
Study Chair: Adriana Andrade, MD, MPH Johns Hopkins University
Study Chair: Edgar T Overton, MD University of Alabama at Birmingham

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