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VSL#3 Induces Remission for Ulcerative Colitis

VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis.

An article published in the National Library of Medicine National Institute of Health last year showed that the results of a human clinical for the treatment of patients with mild to moderate Ulcerative Colitis. Patients were given VSL#3 for 6 weeks. At the end of the 6 week period those patients had a remission rate of 77% with no adverse side effects.

VSL#3 Probiotics

VSL#3 Probiotics

How Does VSL#3 Probiotic Work?

Many probiotic formulas contain beneficial bacteria, but due to differences in types of bacteria and preparation of the products, these bacteria die off from varying conditions throughout the GI tract and never make it to the place they need to be. Studies shows that probiotics from VSL#3 do make it to the colon, which is the area they need to reach to be effective.

A study conducted with VSL#3 confirms that maximum bacterial colonization of the gut occurs within 20 days.

Prebiotic Fiber with PHGG

Prebiotic Fiber

It’s not really one of those things where you can just take it for a few weeks and think you are good to go. You are essentially adding new bacteria to your gut to recolonize it.

We find most of our clients have the greatest success when pairing VSL#3 with a prebiotic fiber containing partially hydrolyzed guar gum to help feed the probiotics so they grow and multiply in numbers.

Another study conducted on children with Ulcerative Colitis also showed promising results. One 4 week study, conducted on children with UC, found that after the 4 week period where treatment included steroid therapy along with either VSL#3 or placebo, 92.8% in the VSL#3 group achieved remission, compared with only 36.4% in the placebo group.

To maintain the remission, the researchers gave the children 5-ASA along with either VSL#3 or placebo. They then monitored the children over the next 12 months, and found that 73.3% of those who had 5-ASA and placebo experienced a relapse, compared with only 21.4% of those who were taking 5-ASA and VSL#3. This study also reported no adverse side effects from VSL#3.

For more studies on VSL#3 helping with management of Ulcerative Colitis click here. 

Five Reasons Why You May Need to Boost Your Immune System

Have you had a hectic week? If so, your immune system may need a little TLC to get back to functioning properly and protecting you.

What do I mean by a hectic week?

  • Excess Stress
  • Lack of sleep
  • Poor diet
  • No time to exercise
  • Too busy to take your multi-vitamin
We have all been there. Sometimes due to life circumstances our health takes the back seat.
Don’t let that cause you to feel fatigued, run down or end up with a cold.
Maybe you have been sick or recently took a course of Antibiotics.
If any of these ring true to you…you should assume your immune system is weakened.
What can you do to immediately start boosting your immune system?

Give your Immune System a boost with Essential Vitamin & Mineral Multi spray.

Right now take advantage of our special on Vitamin Sprays, buy two & take 50% off the second spray.

It’s so easy to use, just throw one in your purse, backpack or car and take a few sprays whenever it’s convenient. 

How does it work?

When vitamins are sprayed directly into the mouth they are absorbed instantly through the mouth lining, side-stepping the digestive tract completely. 

Literally within seconds it’s delivered via the bloodstream to the various parts of the body for immediate use. 

Oral vitamin sprays has been shown to be up to 9 times more effective than swallowing pills or capsules.

How does your immune system become compromised?

  • Stress

When your body is reacting to emotional or mental stress it produces cortisol hormones. You may have heard of Fight or Flight. You need this for survival. This is okay on a short term basis but over time, when your stress is chronic, these extra cortisol hormones will put you at risk for high blood pressure, heart disease, digestive problems and a weak immune system. Your body will be in  a constant inflammatory state which weakens your immune system.

How does this work?

Your body is not putting energy into fighting a cold or healing because it’s just trying to survive. This is extremely taxing on our immune systems if it’s your chronic state.

If you don’t already meditate try out some techniques from an on-line Stress Management Program or even download a free meditation app on your phone. As little as five minutes a day can make a difference. Studies show that that when your body is in a calm relaxed state your immune function is increased.

  • Lack of Sleep

Research shows that not getting adequate sleep and even a short term loss of sleep has a significant impact on how the immune system functions. 

Recent research conducted by the University of Washington Health Sciences/UW Medicine found that sleep deprivation has the same effect on your immune system as physical stress.

In one study conducted 15 people stayed awake for 29 hours and their white blood cells were measured. What they found is that their immune system become hyperactive and produced elevated levels of white blood cells, the amounts were typical of what you would expect if you had an illness or disease.

Optimize your sleep and commit to at least 8 hours a night.

  • Poor diet 

You know that a whole foods diet with a variety of vitamins and minerals is the best way to have a healthy immune system but is not always possible. The fact is when we eat processed foods or those with too much salt, sugar and saturated fat, it really messes with the entire ecosystem!

Junk food causes the wrong bacteria and yeast to grow.

When your gut bacteria tilts towards a greater amount of bad bacteria you have less of the good bacteria. These trillions of microbes are what make up your immune system.

90% of your immune system resides in our gut.

This is why poor digestion goes hand in hand with weakened immune function and you aren’t able to fight off bugs like the cold and flu the way you should. Try supplementing with a reputable probiotic to tip the scale to the good bacteria.

  • Lack of exercise

Reduced exercise can cause your body to feel lethargic and run down. Movement can support your bodies natural detoxification process, keep your lymph moving, and give a natural boost to a weak immune system.

  • Not supplementing with a multivitamin 

Not getting adequate amounts of Vitamins, minerals and nutrients from your diet can lead to a depressed immune system. Take a multivitamin to fill in nutritional gaps. We recommend Perfect Pass Immune Formula. It comes in powder form or capsules.

If you have a hectic lifestyle and find you are constantly juggling work, children, families or school, just pick up a bottle of Essential Multi Vitamin & Mineral Spray and throw it in your bag. Anytime you feel your immune system could be compromised take a few sprays. It’s so convenient.

Why VSL3?

VSL#3 Probiotic 2 Pack Capsules VSL3 Can Help If You….

  • Have heavy stress
  • Have recently taken antibiotics
  • Drink a lot of alcohol
  • Eat a lot of sugar
  • Get recurring fungal infections

Did you know that if you do just one of these system stressors on a regular basis, your gut health could be compromised.  Microorganisms which reside in your gut can not be stimulated to grow by a change in diet alone. That’s why probiotics are necessary. Before your immune system gets out of wack, consider taking probiotics.

Why take VSL#3?

  • 10 times the strength of the average probiotic
  • Proprietary blend of 8 strains of live probiotic bacteria; multiple bacteria strains taken simultaneously provide a wider range of benefits than single strain probiotics.
  • The effects of probiotics are very strain specific; the strains of VSL#3 are backed by more than 170 published studies
  • Greater potency which ensures that bacteria survive the stomach acid and bile to colonize in your gut.
  • VSL #3 is now dairy-free for those people who suffer from milk allergies or lactose intolerance.

In 2014 the World Health Organization defined Probiotics as “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host.” VSL#3 meets the definition of a probiotic.

What are the results of VSL#3?

  • Maintains a healthy mucosal lining
  • Strengthens intestinal barriers
  • Strengthens the tight junctions
  • Improves immune system
  • Improves digestion

What Conditions Does VSL#3 Help?

If you are still wondering if VSL#3 could be right for you, take a look at these testimonials from those who have been helped by this product. VSL#3 is now available in three formulations, regular strength, double strength and packet form. It’s simple to take as a capsule or just add it to a beverage or smoothie.

Contact us if you have any questions about VSL#3 or need help with determining the best dose to take for your condition or symptoms.

VSL#3 Probiotic is now Dairy Free

VSL#3 Probiotic is now Dairy FreePress Release provided by PR Newswire tells us that VSL3 Probiotic is now Dairy Free. This has not been the case up until their recent move of manufacture to Italy.

VSL#3 Probiotics representative has announced that VSL Pharmaceuticals has relocated the manufacture of their probiotic medical food VSL#3 back to Italy so that they can remove all traces of dairy from the process. According to their press release it makes them the only dairy-free probiotic medical food available.

What is VSL#3 Probiotic?

The press release goes on to explain that VSL#3 (VSL Pharmaceuticals) is a probiotic medical food for the dietary management of patients with ulcerative colitis, irritable bowel syndrome and ileal pouch.

They say that the move to make it diary-free will enable those patients who also suffer from milk allergies or lactose intolerance to be able to use VSL#3.

Mary Ocnean, vice president of commercial operations at Sigma-Tau Healthscience USA Inc., VSL#3’s U.S. distributor, says, “As demand for the VSL#3 brand continues, we have more consumers and recommenders talking about VSL#3 and giving us great feedback over the years, including some questions around the dairy component.”

“Moving VSL#3 back to the original manufacturing facility in Italy allowed the brand to revert back to an established process that removes all dairy while maintaining the original proprietary mix of eight strains of live bacteria.”

“The new manufacturing process will also be more efficient and stabilize pricing.”

She says that the relocation will enable packaging improvements to help maintain potency, including a new cap to replace the peel-off covering, and they are using thicker powder packets or sachets.

Ocnean adds that a trace amount of cornstarch has also been added to the product to reduce moisture and maintain potency,. This may be an area of concern for those patients who have corn allergies and previously used VSL3 capsules or their discontinued flavored packets that did not contain corn starch before the change was made to making VSL3 dairy-free.


New Probiotic Visbiome is Here

This new probiotic formulation is not really new at all. In fact, Professor Claudio De Simone invented the formulation in the mid-1990s, and it’s been on the market under the “VSL#3®*” brand name since 2003.  In early 2015, Professor De Simone began collaborating with ExeGi Pharma, LLC to produce Visbiome.  Visbiome  contains the same formulation as is found in the VSL#3®* probiotic blend as produced before January 31, 2016. VSL#3® is a registered trademark of, and is manufactured exclusively for, VSL Pharmaceuticals, Inc. Visbiome is manufactured exclusively for ExeGi Pharma, LLC and is not affiliated with, endorsed by, or distributed by VSL Pharmaceuticals, Inc.

That’s right, Visbiome contains the same probiotic blend, and is manufactured using the original production methods, that the Professor originally invented, but it is priced lower than VSL#3.

Visbiome ProbioticIf you have used VSL#3* for relief from digestive conditions then you know how effective it is.

Recently, Professor Claudio De Simone, released an informative open letter to healthcare practitioners . . . 

Visbiome Letter

Dear Colleagues,

As a healthcare practitioner caring for patients with complex conditions like inflammatory bowel disease, ulcerative colitis and ileal pouch, you know that prescribing multi-strain, high-potency probiotics can be an important tool in stabilizing your patients’ conditions. As a gastroenterologist and Associate Professor of Infectious Diseases at the Department of Medicine and Surgery of the University of L’Aquila in Italy, I am writing to update you on an important new development.

Nearly 25 years ago, I invented a high-potency probiotic formulation, which was later sold under the brand name, “VSL#3®*.” This brand name was registered as a trademark by VSL Pharmaceuticals, Inc., and my formulation has been sold for years as a medical food under that trademark.

Now, my proprietary formulation (the “De Simone Formulation”) is available under the trademarks, “Visbiome™” and “Visbiome™ Extra Strength.” Recently, I entered into a partnership with ExeGi Pharma, LLC to produce and commercialize my formula. Visbiome is manufactured for ExeGi Pharma, LLC and is not affiliated with, endorsed by, nor distributed by VSL Pharmaceuticals, Inc.

While I retain full ownership of the De Simone Formulation, VSL Pharmaceuticals, Inc. retains ownership of the “VSL#3®*” trademark. Because of this unusual situation, my goal is to ensure that doctors and patients have a clear understanding of the formulation found in Visbiome. You and your patients therefore should rest assured that Visbiome does indeed contain the De Simone Formulation (i.e., the same strains, in the same concentrations and proportions, and is therapeutically equivalent to the VSL#3®* probiotic blend produced before January 31, 2016).

As a scientist and physician, I am extremely proud of the vast amount of clinical data that has been gathered on the De Simone Formulation over the past 25 years. That is why I have worked to ensure absolute consistency in the manufacture of my formulation, now found in Visbiome.

Because ExeGi has adhered to the original composition of strains, methods of production (both fermentation and lyophilization), and strain ratios, you can be confident that the extensive body of research on the De Simone Formulation will be applicable to your clinical decision-making about whether Visbiome is right for your patients.

Many of you in the GI community have been generous over the years in sharing how the De Simone Formulation has helped many of your patients manage their conditions. This extraordinary record of therapeutic success has fueled my commitment to ensuring that your patients will have continued and expanded access to the formulation they have come to trust and depend on for a quarter century. For this reason, I’m very pleased to announce that ExeGi will be manufacturing the De Simone Formulation exactly as it has been produced for so many years.

Claudio De Simone, M.D., PhD

*VSL#3® is a registered trademark of VSL Pharmaceuticals, Inc. and is manufactured exclusively for, VSL Pharmaceuticals, Inc. Visbiome is manufactured exclusively for ExeGi Pharma, LLC and is not affiliated with, endorsed by, nor distributed by VSL Pharmaceuticals, Inc.

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