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Probiotics Symposium Day 3

Probiotics Symposium Day 3

This has certainly been three VERY full days in San Antonio TX …..
– full of valuable information in the area of probiotics and how they relate to literally all fields of medicine and do you know why? There are more neurotransmitters in your gut than there are in your head and so if probiotics feed the microbiomes that live in your gut, there isn’t an area of your body’s function that will be not benefit.
-also full of presenters and colleagues who are experts in their fields. The cacophony of sound at the luncheon tables were a true indication of how much communication was taking place… everyone was so open to sharing their knowledge and experiences with others… what a pleasure.

The Alamo San Antonio TXIt was only later in the day, my last day, that I reminded myself that I had not been down to visit ‘The Alamo’! Imagine visiting San Antonio and not going there! I remedied that rather quickly by taking a quick sprint down E Houston Ave and was there in 8 minutes! And what a splendid experience – I was so happy I did – I learned so much US history that I didn’t know about.

Gerard Mullin MD, Assoc Prof of Medicine at John Hopkins University School of Medicine was our first presenter, talking about “Gi microbiota in Obesity”. Did you know that you cut your life by 10 years when you have morbid obesity? wow! and of course there are HUGE costs to US relating to obesity.

What did he teach me today? ….that the human microbiome is made up of a community ofGerard E Mullin MD Obesity microbes that can actually collectively sense one another! And we feed them with the food we eat.These Gut microbiota are a very important consideration with regard to obesity and are referred to as ‘fat bugs’ and what happens in obesity is that there are distorted microbiomes due to an imbalance. You see there are two kinds, Furmicutes and Bacteroidetes – Furmicutes are fat forming (not good) and then there are
Bacteroidetes and those are more of what you want.

Experiments with mice show that fat mice have lots of Furmicutes and if donor stool is from fat mice the experimental mice will get fat. The studies are done using FMT – Fecal Microbial Transplants. Mullin also discussed how high fat sugar alters the composition of bacteria flora that leads to increase in firmicutes and fewer bacteroidetes and this affects metabolism.

Next was Maria M Oliva-Hemker MD, who specializes in Pediatric Gastroenterology & Nutrition, and is a Stermer family professor of Pedriatric IBD, at John Hopkins University School of Medicine in Baltimore MD, She was a very fluent and interesting presenter. She deals a lot with babies who suffer with intestinal micro necrotizing enterocolitis, a life threatening inflammatory intestinal disorder in infancy. She says that prophylaxis of chronic disease starts with infant and child. She sited lots of experiments that are on the way. One comment she made was to consider giving the mom more probiotics during on pregnancy.

I had listened to Elizabeth Mumper MD speak in Alexandria, Virginia last year. She runs the Rimland Center for Integrative Medicine and Advocates for kids and families. Her topic was “Gi Disturbance in Kids with Autism”. I was amazed to hear Dr Mumper’s most recent statistics that autism spectrum disorder is currently affecting 1 in 50 kids in the US.

Diarrhea and constipation are recurrent associated symptoms in autism and probiotics Elizabeth Mumper MDare very prevalent in her practice. Probiotics enhance killer cell IGA and so helps generally with digestion. She stressed how each child is unique and needs to be treated individually. She says that often behavioral disturbance is a sign of the expression of pain in a non-verbal child. She sees many children with leaky gut and recommends zinc as an important supplement for helping with this condition. She also recommends SCD Breaking the Vicious Cycle diet, explaining that Gluten is not recommended for these kids, not only because of possible celiac complications, but rather because there is a pro-inflammatory molecule in gluten and will manifest often as IBS. She mentioned that she always puts her patients on essential fatty acids

She commented on the differences in autism, ulcerative colitis and crohns, saying that even though they resemble each other and overlap in many ways, their gene expression is different. She regards the symptoms of eczema as much more than a skin condition to be treated with topical creams, to her its the window to the immune system. She spoke about how often she sees kids who have been on excessive bouts of antibiotics in the first 12-18 months of their life and this will wipe out all their good bacteria and add fuel to the fire.

Stephen Olmstead presented a very contraversal topic “Helicobacter pylori – Foe? Dr Stephen Olmstead MDSometimes Friend? He explained how H pylori is thought to be a monstrous organism that causes cancer and we need to get rid of them. Yet perhaps not??? He says that H pylori has been cohabiting with humans beings for 150 thousand years and that they modulate gastric output as well as encourage acid homeostasis.

H pylori was first identified by Dr Warren as a spiral bacteria 1979.Then in 1981 Drs Warren and Marshall collaborated and in 1985 actually won the Nobel prize for their pioneering work. Its a gram negative bacteria with 2-8 flagellae and can invade epithelial cells. It may be spread orally in water and by domestic pets.

H pylori is a commensal gastric organism. Yes, its pathogenic in 15-20 % people. But maybe it ought to be there but in small amounts?? We have been treating ulcers with h pylori but now we notice that there is an increase in esophageal cancer. why? Also, is there increase in asthma because of treatment of h pylori? These are the unanswered questions.

Treatment often fails, he says, and antibiotics are usually necessary.Why?
Dr Olmstead points to Biofilm where he feels the h pylori resides and hence the reason that its so difficult to eradicate. S boulardii has been shown to damage h pylori structure.
When used alone it only shows effective in small numbers – you use 10 billion cfu per day. Take for 30 days. Certainly natural agents are anti biofilm, like enzymes, probiotics and N acetyl l cysteine. These supplements are extremely helpful in dissolving Biofilm and I can order them for you from Klaire Labs – please email pamela@crohns.net or call 877-240-7528.

I really enjoyed meeting naturopath, Amy Johnson, whose practice is in Portland, Oregon. We discovered that we both practiced homeopathy which immediately added another area of conversation for us. She helps lots of people with digestive complaints teaching them about ‘the elimination diet’. She even offers cooking classes to her patients which makes compliance that much easier for them. Check her out at BlueHouseHolisticHealth.com

Pamela Nathan & Amy Johnson

 

 

Probiotics Symposium Day 2 – San Antonio TX

Russell Jaffe MDRussell Jaffe MD, Ph D, CCN, Fellow of Health Studies Collegium, was the first presenter today. He had lots and lots of valuable information to share with us. He focused on the importance of what he referred to as ‘qualified predictive biomarkers’ that help us to understand each person’s condition and what needs to be considered when advising treatment.

These are the ‘qualified predictive biomarkers’  that he recommends. The tests are freely available and any physician can order them. If you’re interested in doing so,  just make a note of them and take the list to your favorite physician for the tests to be run and interpreted for you:

  • Hgb A1c evaluation, This parameter reinforces life style choice as being very important and not only genetics.
  • homocysteine is used to evaluate sulphur cycles. He stressed the importance of having enough sulphur foods in your diet , like garlic, ginger, onion, broccoli sprouts, and eggs.
  • hsCRP evaluates the level of inflammation in your body,
  • Oxidized LDL/HDL and 8 oxo-guanine evaluates free radical risk,
  • Vitamin D ensures cell adhesion
  • 1st am urine pH to evaluate acidosis risk
  • LRA by ELISA/ACT tolerance and hypersenstivity test.He says by getting the results from these tested, collectively, you can have a very good idea of how ‘healthy’ a person is, and can anticipate whether they have a chance of living for another 10 or 20 years.

Stig Bengmark MDI loved the quote that Stig Bengmark from Sweden included in his presentation: “We are living in a world today where lemonade is made from artificial flavors and furniture polish is made from real lemons.” He reinforced my belief that underlying persistent inflammation is the mother of all disease. He explained how stressors can turn genes on and off, modify histones and even seem to affect what gets passed down to our offspring.

He sees a relationship between malfunctioning microbiota and dysbiosis where the two go hand in hand. When microbiota are stable they reduce general inflammation and maintain immune homeostasis. When they’re not stable, that’s when we start getting problems. He also said that processed foods can be responsible for encouraging dysbiosis, leaky gut and a malfunctioning immune response.

He spoke about the importance of eating magnesium rich foods, tumeric, and fermented foods. He loves avocados and made the comment that he would suggest mothers feed their infants avocados rather than formula!

Charalabos Pothoulakis MDCharalabos Pothoulakis MD from the Division of Digestive Disease at UCLA gave an in depth talk on what we know currently about saccharomyces boulardii and c difficile, the leading cause of healthcare-infectious diarrhea in the US. He has been involved in studies on saccharomyces boulardii  and they have shown how helpful this friendly strain of yeast has been in the prevention and treatment of diarrhea that has been caused by antibiotics and also c difficile. Another study he spoke about was conducted on Crohn’s patients. They found that  S. boulardii added to baseline therapy reduced leaky gut and improved intestinal permeability in these patients. (Gracia Vilela et al 2008,43(7):842-8)

Michael Cabana MDMichael Cabana MD from UCSF told us about the use of probiotics with pediatric allergies and asthma patients. He wasn’t able to site any conclusive evidence as some studies showed positive outcomes while others didn’t – it may have to do with patient compliance, he said, and will need to be studied further. He did say that they have found the probiotic,  l. reuteri to be used effectively for colic.

There were questions from the audience with regard to FMT – Fecal Microbial Transplants. Dr Cabana told us that presently the procedure was conducted in Seattle, Washington and Canada. He was hopeful that it would be used more extensively in the future, in the US, as there was a CPT code assigned to the procedure!

Probiotics Symposium Attendees

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