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Genova’s GI Effects Stool Test is the Best

I’m sold on Genova Lab’s GI Effects Stool Test.  It really is the best …and I’ll tell you why.

I’ve been using this lab for over 30 years now, if you can believe that.  They’ve really made great strides in staying up-to-date by including state-of the-art testing options in this test. I started using GI Effects profile a lot recently and find it to be extremely informative.

In previous years, their stool tests that  I ran for my patients were cultures only. Now they make use of PCR testing as well. You see anaerobic organisms don’t grow in culture, so having DNA testing is far more accurate.

What is PCR testing?

DNA Sequencing used in GI Effects Stool test
PCR stands for Polymerase Chain Reaction.

It is used to amplify selected sections of DNA or RNA for analysis. Previously, this procedure required cloning of the segments of interest into vectors for expression in bacteria. It took weeks.

But now, PCR is done in test tubes. It only takes a few hours. This means that this advanced stool test is able to provide immediate, actionable clinical information.

It helps in evaluating the course of action needed to manage various types of gut conditions like irritable Bowel Syndrome IBS, Crohns, Colitis IBD and other Malabsorption Disorders

Their PCR molecular assay is optimized for stool testing. It assesses 24 commensal bacteria associated in scientific literature with health and disease. It gives us valuable insight into the human microbiome.

I’m also very impressed by the enhanced test reporting that they do. On the very first page there’s an overview that you can understand at a glance. It highlights biomarkers in three main areas of gut health: Infection, Inflammation, and Metabolic Imbalance. This makes it very easy for lay people to understand and to see what areas need attention.

I also like that the GI Effects Comprehensive Profile includes very important markers:

(a) Calprotectin.
This is an invaluable biomarker that can effectively differentiate between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD).

(b) Ova & Parasite Detection.
They use the gold standard for parasite identification.

You can choose as to whether you want a 1 or 3 day collection, based on how likely there is an issue relating to parasitic infection.

If low or no suspicion of parasites, then a one day sample is adequate.

Only if there is a high likelihood of parasites that a 3-day sample collection is needed.

Add-On Options to GI Effects Stool Test

I like the way they make certain valuable add-ons available.

Some pathogenic bacteria testing can be extremely expensive. So, by excluding them in the original test, but offering them as ‘add-on’s’ is a great idea.

The specific bacteria add-on tests that can be run are:

  • Clostridium difficile,
  • Campylobacter,
  • Escherichia coli EIA,
  • Helicobacter pylori EIA and
  • Fecal Lactoferrin.

Zonulin Tests for Intestinal Permeability

Their most recent add-on is Zonulin.

Zonulin is a protein modulator of intestinal tight junctions that is used to assess intestinal permeability.

Up until now, the only way we could test for intestinal permeability was by using a stand alone test … another expense and not a very pleasant procedure.

We had to drink pre-measured amounts of lactulose and mannitol and then evaluate the degree of intestinal permeability or malabsorption that was reflected in the levels of the two sugars recovered in a urine sample that needed to be collected over the next 6 hours.

We know from recent peer-reviewed literature about the significant role that intestinal permeability plays in many chronic gut problems, particularly Leaky Gut with symptoms like bloating, gas and cramps.

Intestinal Permeability will also have an impact on IBS, food sensitivities, joint pains, skin rashes and auto immune conditions.

Then there’s added problems associated with intestinal permeability for Cardio-metabolic diseases like type 1 and 2 diabetes, obesity, non-alcoholic fatty liver disease, and even insulin resistance.

Being able to add the Zonulin test on to the GI Effects Profile is a win. One less test, added financial savings and less hassle.

 

Dr. Ohhira’s Probiotics are Premium

Dr. Ohhira’s: The World’s Best Premium Probiotic

Ross Pelton -The Natural Pharmacist

Ross Pelton -The Natural Pharmacist

Ross Pelton, the author of this article, happens to be one of the first people I met when I came to live in the United States 37 years ago. He is currently the Scientific Director for Essential Formulas who distribute Dr. Ohhira’s probiotics that we recommend to many of our patients. He is a pharmacist and a true expert on pharmaceutical drugs and their life-altering side effects. He is also a clinical nutritionist and helps people with diet, nutrition and natural therapies. He truly is an expert in helping his clients integrate the best of both worlds to achieve improvment in their health.

Here’s an article that he published in April of this year. Check him out on Facebook, The Natural Pharmacist.

He writes:
Dr. Ohhira’s probiotics are the world’s most popular premium probiotic supplement and the most effective product to remodel and optimize functioning to the human gastrointestinal tract. It has won numerous International Supplement Awards, including Best Supplement Award, by Better Nutrition Magazine for six consecutive years running. I want to explain the reasons why Dr. Ohhira’s probiotics are so unique.

Fermentation:

Dr. Ohhira’s probiotics are allowed to grow in huge fermentation vats (shown above) for three (Original Formula) or five years (Professional Formula). During this time, the bacteria are producing a wide range of nutrients and immune system enhancing compounds that other probiotic products don’t begin to produce until they get established in the GI tract. Along with the beneficial bacteria, each capsule of Dr. Ohhira’s contains a therapeutic dose of immune system enhancing compounds. No other probiotic product in the world is produced using this type of fermentation process for the bacteria.

Multi-strain product: Dr. Ohhira’s probiotics contain 12 synergistic strains of beneficial bacteria. Because individual strains of bacteria provide different biological functions, a multi-strain product can provide a broader range of benefits.

Proprietary Enterococcus faecalis TH10: This is a strain of lactic acid-producing bacteria that was discovered by Dr. Ohhira and is only available in Dr. Ohhira’s probiotic products. TH10 is one of the strongest anti-microbial probiotics that has ever been discovered. To date, TH10 has proven to be over 6 times stronger than any other known strain of bacteria.

Prebiotics:

Prebiotics are compounds that are “food” for the probiotic bacteria. A blend of 92 nutrition-rich fruits, vegetables, seaweeds and mushrooms are periodically added to the fermentation vats at seasonally appropriate times which provides the growing strains of probiotic bacteria with unique natural energy-rich prebiotic food supply. When encapsulated, each capsule of Dr. Ohhira’s contains the beneficial strains of probiotic bacteria plus the nutrient-dense prebiotics which allow the bacteria to thrive. No other probiotic product provides such a rich supple of prebiotic ingredients along with the probiotics.

Organic acids:

One of the important functions of probiotics is the production of compounds called short-chain fatty acids (SCFAs) such as lactic acid, acetic acid, propionic acid and butyric acid. These weakly acidic compounds create a slightly acidic environment in the intestinal tract which is the optimal condition to support the growth of beneficial bacteria while inhibiting the growth of pathological bacteria. The strains of bacteria in Dr. Ohhira’s probiotics have been shown to be strong producers of these organic short-chain fatty acids.

No refrigeration:

Because the fermentation process takes place at ambient room temperatures, Dr. Ohhira’s probiotics are stable at room temperature and do not require refrigeration. They have an impressive 3-year stable shelf life.

Patented Capsule Design:

The capsule for Dr. Ohhira’s probiotics is designed to stay hard in the harsh acid environment in the stomach. It then becomes porous in the more alkaline environment in the small intestine. Hence, the probiotics are preferentially released in the small intestine where they begin to provide their wide range of health benefits.

Effective Against Pathogens:

Dr. Ohhira’s probiotics have been shown to be effective several key pathogens including the cancer-causing bacteria Helicobacter pylori (H. pylori) and Clostridium difficile or C. diff. Also, in cell culture studies, Dr. Ohhira’s probiotics have been shown to kill MRSA which is the abbreviation for methicillin-resistant staphylococcus aureus. MRSA is currently a serious global health crisis because it has become resistant to nearly all antibiotics. So, Dr. Ohhira’s, which are non-prescription over-the-counter probiotics have been shown to be effective against some of the world’s most serious pathological organisms.

Other Benefits:

Dr. Ohhira’s probiotics are also non-GMO, non-dairy, gluten-free and 100% vegan.

Source:
The Natural Pharmacist
Posted April 20, 2015

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