Probiotic for Periodontal Disease
A study that was published in the Journal of Periodontology 2915;86:746-754 references 30 patients who had chronic periodontitis and moderately deep pockets who were treated with scaling and root planing.
They were randomly assigned to receive, using a double-blind model, either probiotic lozenges two times a day, morning and evening after brushing their teeth, or placebo lozenges for 3 weeks. The probiotic lozenges contained Lactobacillus reuteri strains DMS17938 and ATCC PTA 5289.
Evaluations were performed at baseline and then again on days 21, 90, 180, and 360.
Compared to the placebo, probiotic treatment showed significant improvements in several periodontal disease markers like plaque index, gingival index, bleeding on probing, probing depth, and attachment gain at every time point.
Biochemical studies on gingival crevicular fluid showed a reduction in inflammatory markers in the probiotic group
What was also significant, the beneficial effect of the probiotic lozenges persisted long after the treatment was discontinued, which may be related to the alteration of the oral bacterial flora.
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