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New Probiotic Visbiome is Here

This new probiotic formulation is not really new at all. In fact, Professor Claudio De Simone invented the formulation in the mid-1990s, and it’s been on the market under the “VSL#3®*” brand name since 2003.  In early 2015, Professor De Simone began collaborating with ExeGi Pharma, LLC to produce Visbiome.  Visbiome  contains the same formulation as is found in the VSL#3®* probiotic blend as produced before January 31, 2016. VSL#3® is a registered trademark of, and is manufactured exclusively for, VSL Pharmaceuticals, Inc. Visbiome is manufactured exclusively for ExeGi Pharma, LLC and is not affiliated with, endorsed by, or distributed by VSL Pharmaceuticals, Inc.

That’s right, Visbiome contains the same probiotic blend, and is manufactured using the original production methods, that the Professor originally invented, but it is priced lower than VSL#3.

Visbiome ProbioticIf you have used VSL#3* for relief from digestive conditions then you know how effective it is.

Recently, Professor Claudio De Simone, released an informative open letter to healthcare practitioners . . . 

Visbiome Letter

Dear Colleagues,

As a healthcare practitioner caring for patients with complex conditions like inflammatory bowel disease, ulcerative colitis and ileal pouch, you know that prescribing multi-strain, high-potency probiotics can be an important tool in stabilizing your patients’ conditions. As a gastroenterologist and Associate Professor of Infectious Diseases at the Department of Medicine and Surgery of the University of L’Aquila in Italy, I am writing to update you on an important new development.

Nearly 25 years ago, I invented a high-potency probiotic formulation, which was later sold under the brand name, “VSL#3®*.” This brand name was registered as a trademark by VSL Pharmaceuticals, Inc., and my formulation has been sold for years as a medical food under that trademark.

Now, my proprietary formulation (the “De Simone Formulation”) is available under the trademarks, “Visbiome™” and “Visbiome™ Extra Strength.” Recently, I entered into a partnership with ExeGi Pharma, LLC to produce and commercialize my formula. Visbiome is manufactured for ExeGi Pharma, LLC and is not affiliated with, endorsed by, nor distributed by VSL Pharmaceuticals, Inc.

While I retain full ownership of the De Simone Formulation, VSL Pharmaceuticals, Inc. retains ownership of the “VSL#3®*” trademark. Because of this unusual situation, my goal is to ensure that doctors and patients have a clear understanding of the formulation found in Visbiome. You and your patients therefore should rest assured that Visbiome does indeed contain the De Simone Formulation (i.e., the same strains, in the same concentrations and proportions, and is therapeutically equivalent to the VSL#3®* probiotic blend produced before January 31, 2016).

As a scientist and physician, I am extremely proud of the vast amount of clinical data that has been gathered on the De Simone Formulation over the past 25 years. That is why I have worked to ensure absolute consistency in the manufacture of my formulation, now found in Visbiome.

Because ExeGi has adhered to the original composition of strains, methods of production (both fermentation and lyophilization), and strain ratios, you can be confident that the extensive body of research on the De Simone Formulation will be applicable to your clinical decision-making about whether Visbiome is right for your patients.

Many of you in the GI community have been generous over the years in sharing how the De Simone Formulation has helped many of your patients manage their conditions. This extraordinary record of therapeutic success has fueled my commitment to ensuring that your patients will have continued and expanded access to the formulation they have come to trust and depend on for a quarter century. For this reason, I’m very pleased to announce that ExeGi will be manufacturing the De Simone Formulation exactly as it has been produced for so many years.

Claudio De Simone, M.D., PhD

*VSL#3® is a registered trademark of VSL Pharmaceuticals, Inc. and is manufactured exclusively for, VSL Pharmaceuticals, Inc. Visbiome is manufactured exclusively for ExeGi Pharma, LLC and is not affiliated with, endorsed by, nor distributed by VSL Pharmaceuticals, Inc.

Copyright © 2016 Good Gut Solution.

Sheryl Cohen June 10, 2016