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VSL3# Probiotic
Clinical Trials
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VSL#3 Frequently Asked Questions

Why VSL#3?

VSL#3 is a patented combination of live lactic acid bacteria probiotics that have been cultivated, freeze-dried and mixed in high concentration (hundreds of billions per gram).

VSL#3 is the probiotic that has been proven in clinical studies to be effective in serious gastro-intestinal disorders, and in particular in the management and preventions of pouchitis. Pouchitis, an inflammation of the small bowel reservoir or pouch, is the most frequenet long-term complication following colon removal and pouch creation surgery for ulcerative colitis.

VSL#3 has the highest possible concentration of bacteria. Each packet of VSL3 contains 450 billion live lactic acid bacteria. This high number is necessry to ensure the establishment of lactic acid bacteria in the gut andf trigger the desired effects in the intestinal tract.

VSL#3 science speaks for itself. 8 strains of bacteria have been purposefully selected, carefully cultivated and mixed proportionately to obtain the proven experimental and clinical effects of VSL#3:

• Bifidobacterium breve
• Bifidobacterium longum
• Bifidobacterium infantis
• Lactobacillus acidophilus
• Lactobacillus plantarum
• Lactobacillus casei
• Lactobacillus bulgaricus
• Streptococcus thermophilus

Is VSL3 Safe?

Clinical studies have shown that VSL3 probiotics can be taken safely for long periods of time without any problems. Adjustment of the intestinal flora after VSL3 administration can take a few days or weeks and it can take up to a month for the colonization of the gut to become optimally stable.

What makes VSL3 unique?

VSL3 is unique in 4 ways:

1. VSL3 is the probiotic proven effective in controlled clinical trials.
2. VSL3 has a high concentration for a total of 450 billion live lactic acid bacteria per packet.
3. VSL3 contains 8 beneficial strains acting like a 'Living Shield'. When comparing other available products, you should consider the number of strains and the total bacteria.
4. VSL3 is reasonabley priced when considering the number of lactic acid bacteria you get per dollar.

How should I take VSL3?

VSL3 probiotics may be mixed with yogurt, ice-cream, apple sauce or any other cold food or non-carbonated drink. Stir the contents and ingest immediately. VSL3 should not be mixed or taken with hot foods or hot drinks as the high heat inactivated the live lactic acid bacteria.

Will I feel immediate benefits from VSL 3?

Depending on your condition and the dose of VSL 3 helpful bacteria you are taking, the effects may not be seen until the intestinal tract adjusts. Clinical studies show that colonization in the gut may take up to 1 month.

Do lactic acid bacteria in VSL 3 permanently colonize the gut?

Clinical trials indicate that after discontinuation of VSL 3the number of lactic acid bacteria in the gut generally returns to previous levels in about 2-3 weeks. In certain conditions you may need to take VSL 3daily in order to maintian beneficial effects.

How much VSL#3 should I take?

The dosage depends on many factors and individual results may vary.

Clinical studies suggest the following guidelines:

Bowel Movements per day	VSL3 packets per day
more than 8	4
between 5-8	2-4
less than 5	1-2

VSL3 Research Studies

See VSL#3 Animal Model Studies

VSL#3 Probiotic Studies by Dr Fedorak

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