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Crohn's Disease- Pathophysiology and Conventional and Alternative Treatment Options


Table 2. Signs and Symptoms of Crohn's Disease and Ulcerative Colitis

Sign/Symptom Crohn's Disease Ulcerative Colitis
Area of intestinal tract affected Lower ileum most common but can flare up anywhere, including the colon; "patches" of normal tissue between affected areas: can affect entrie intestinal wall Any part of inner most lining of colon, continues with no "patches" of normal tissue
Diarrhea Typically four or more episodes per day Typically four or more episodes per day
Abdominal pain/cramping Moderate to severe abdominal tenderness in right lower quadrant Mild tenderness, lower abnominal cramping
Blood in stool Present; amount depends on disease severity Present; amount depends on disease severity
Fatigue Result of excessive blood loss, anemia, and poor nutrient absorption Result of excessive blood loss and anemia
Fever Low-grade in severe cases Low-grade in severe cases
Physical examination Peritoneal irritation, abdominal or pelvic mass Rectal exam may show peri-anal irritation, fissures, hemorrhoids, fistulas, and abscesses
Weight loss/anorexia Weight loss and anorexia common due to poor digestion and intestinal absorption Weight loss in more severe cases
Appetite Often decreased during periods of disease exacerbation Often decreased during periods of disease exacerbation
Risk of colon cancer Increased Increased




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